Alberto Maria Luciano

Full Professor


Professor of Veterinary Anatomy and Embryology at the University of Milan. He earned a M.Sc. in Biological Sciences and a Ph.D. in Biotechnology applied to Veterinary Medicine and Animal Sciences at the University of Milan. In John Peluso’s Lab, he undertook a postdoctoral fellowship in Reproductive Physiology at the University of Connecticut, School of Medicine, CT, USA, studying the role of progesterone in regulating granulosa cell apoptosis. The current research topic focuses on mammalian oocyte differentiation and on cellular and molecular determinants that confer oocyte meiotic and embryonic developmental competence. Co-founder of the Reproductive and Developmental Biology Laboratory, which has coordinated since 2005.


Recent Peer-reviewed Research Publications (last 5 years)

  1. Dey P, Monferini N, Donadini L, Lodde V, Franciosi F, Luciano AM. Method of Isolation and In Vitro Culture of Primordial Follicles in Bovine Animal Model. In: Barchi M, De Felici M (eds.), Germ Cell Development: Methods and Protocols. New York, NY: Springer US; 2024: 171-182.
  2. Riva F, Filipe J, Pavlovic R, Luciano AM, Dall’Ara P, Arioli F, Pecile A, Groppetti D. Canine amniotic fluid at birth: From a discarded sample to a potential diagnostic of neonatal maturity. Anim Reprod Sci 2023; 248:107184.
  3. Nenonene EK, Trottier-Lavoie M, Marchais M, Bastien A, Gilbert I, Macaulay AD, Khandjian EW, Luciano AM, Lodde V, Viger R, Robert C. Roles of the cumulus-oocyte transzonal network and the Fragile X protein family in oocyte competence. Reproduction 2023; 165:209-219.
  4. Luciano AM, Franciosi F, Dey P, Ladron De Guevara M, Monferini N, Bonumallu SKN, Musmeci G, Fagali Franchi F, Garcia Barros R, Colombo M, Lodde V. Progress toward species-tailored prematuration approaches in carnivores. Theriogenology 2023; 196:202-213.
  5. Lodde V, Luciano AM, Garcia Barros R, Giovanardi G, Sivelli G, Franciosi F. Review: The putative role of Progesterone Receptor membrane Component 1 in bovine oocyte development and competence. Animal 2023; 17 Suppl 1:100783.
  6. Garcia Barros R, Lodde V, Franciosi F, Luciano AM. A refined culture system of oocytes from early antral follicles promotes oocyte maturation and embryo development in cattle. Reproduction 2023; 165:221-233.
  7. Ebrahimi M, Dattena M, Luciano AM, Succu S, Gadau SD, Mara L, Chessa F, Berlinguer F. In vitro culture of sheep early-antral follicles: Milestones, challenges and future perspectives. Theriogenology 2023; 213:114-123.
  8. Dellaqua TT, Vigaro RA, Janini LCZ, Dal Canto M, Renzini MM, Lodde V, Luciano AM, Buratini J. Neuregulin 1 (NRG1) modulates oocyte nuclear maturation during IVM and improves post-IVF embryo development. Theriogenology 2023; 195:209-216.
  9. Alkali IM, Colombo M, Luciano AM, Nizanski W, Ali Hassan H, Dziegiel P, Luvoni GC. Culture of vitrified bovine ovarian tissue on agarose gel inserts maintains follicle integrity. Reproduction 2023; 166:299-310.
  10. Lodde V, Garcia Barros R, Terzaghi L, Franciosi F, Luciano AM. Insights on the Role of PGRMC1 in Mitotic and Meiotic Cell Division. Cancers (Basel) 2022; 14:5755.
  11. Dey P, Luciano AM. A century of programmed cell death in the ovary: a commentary. J Assist Reprod Genet 2022; 39:63-66.
  12. Luciano AM, Barros RG, Soares ACS, Buratini J, Lodde V, Franciosi F. Recreating the Follicular Environment: A Customized Approach for In Vitro Culture of Bovine Oocytes Based on the Origin and Differentiation State. Methods Mol Biol 2021; 2273:1-15.
  13. Lodde V, Luciano AM, Musmeci G, Miclea I, Tessaro I, Aru M, Albertini DF, Franciosi F. A Nuclear and Cytoplasmic Characterization of Bovine Oocytes Reveals That Cysteamine Partially Rescues the Embryo Development in a Model of Low Ovarian Reserve. Animals (Basel) 2021; 11.
  14. Buratini J, Soares ACS, Barros RG, Dellaqua TT, Lodde V, Franciosi F, Dal Canto M, Renzini MM, Luciano AM. Physiological parameters related to oocyte nuclear differentiation for the improvement of IVM/IVF outcomes in women and cattle. Reprod Fertil Dev 2021; 34:27-35.
  15. Terzaghi L, Banco B, Groppetti D, Dall’Acqua PC, Giudice C, Pecile A, Grieco V, Lodde V, Luciano AM. Progesterone receptor membrane component 1 (PGRMC1) expression in canine mammary tumors: A preliminary study. Res Vet Sci 2020; 132:101-107.
  16. Soares ACS, Sakoda JN, Gama IL, Bayeux BM, Lodde V, Luciano AM, Buratini J. Characterization and control of oocyte large-scale chromatin configuration in different cattle breeds. Theriogenology 2020; 141:146-152.
  17. Soares ACS, Marques KNG, Braganca LGM, Lodde V, Luciano AM, Buratini J. Synchronization of germinal vesicle maturity improves efficacy of in vitro embryo production in Holstein cows. Theriogenology 2020; 154:53-58.
  18. Lodde V, Garcia Barros R, Dall’Acqua PC, Dieci C, Robert C, Bastien A, Sirard MA, Franciosi F, Luciano AM. Zinc supports transcription and improves meiotic competence of growing bovine oocytes. Reproduction 2020; 159:679-691.
  19. Barros RG, Lodde V, Franciosi F, Luciano AM. In Vitro Culture Strategy for Oocytes from Early Antral Follicle in Cattle. J Vis Exp 2020:e61625.
  20. Lodde V, Colleoni S, Tessaro I, Corbani D, Lazzari G, Luciano AM, Galli C, Franciosi F. A prematuration approach to equine IVM: considering cumulus morphology, seasonality, follicle of origin, gap junction coupling and large-scale chromatin configuration in the germinal vesicle. Reprod Fertil Dev 2019; 31:1793-1804.
  21. Terzaghi L, Luciano AM, Dall’Acqua PC, Modina SC, Peluso JJ, Lodde V. PGRMC1 localization and putative function in the nucleolus of bovine granulosa cells and oocytes. Reproduction 2018; 155:273-282.
  22. Tatone C, Di Emidio G, Barbonetti A, Carta G, Luciano AM, Falone S, Amicarelli F. Sirtuins in gamete biology and reproductive physiology: emerging roles and therapeutic potential in female and male infertility. Hum Reprod Update 2018:1-23.
  23. Nordio L, Marques AT, Lecchi C, Luciano AM, Stefanello D, Giudice C. Immunohistochemical Expression of FXR1 in Canine Normal Tissues and Melanomas. J Histochem Cytochem 2018; 66:585-593.
  24. Luciano AM, Sirard MA. Successful in vitro maturation of oocytes: a matter of follicular differentiation. Biol Reprod 2018; 98:162-169.
  25. Luciano AM, Franciosi F, Barros RG, Dieci C, Lodde V. The variable success of in vitro maturation: can we do better? Anim Reprod; 2018: 727-736.