Principal Investigator: Federica Franciosi
Primary Coordinator: Alberto M. Luciano
Scientific Coordinator outgoing phase: Marco Conti, University of California, San Francisco
Project: MateRNA – Somatic cells regulation of maternal mRNA translation in mammalian oocytes
Aim: 1) understand how somatic cells regulate the activation of selected mRNA translation in oocytes; 2) determine if a mis-regulation of mRNA translation accounts for impaired embryo development during reproductive aging; 3) identify the extent to which these mechanisms are evolutionarily conserved in mammals.
